Adrian Alberto Vojnov
CONICET - Argentina
Adrian Alberto Vojnov is researcher at at Pablo Cassará Foundation in the Cesar Milstein Institute and Member of Career Investigators of National Scientific and Technical Research Council (CONICET), in Buenos Aires, Argentina. He received in 1996 the PhD in Chemical Sciences by the School of Natural Sciences (FCEN), Universidad de Buenos Aires (UBA), Buenos Aires, Argentina. From 1997 to 2001 Dr. Vojnov did a postdoc training program, at The Sainsbury Laboratory-John Innes Centre, Norwich, UK, under supervision of Prof. Michael Daniels/ Max Dow working at the project ‘Role of xanthan and glucans from X. campestris in the plant-microbe interaction’. He is specialist on plant-microbe interaction research area focusing citrus-xanthomonas citri as model. Besides his research activity, Dr. Vojnov is invite Professor of Molecular Phytopathology at FBMC ( Facultad de Cincias\s Exactas y Nat. UBA.
Summary of lecture
Biofilm formation and virulence factors of Xanthomonas citri subsp. citri associated to canker development in citrus plants.
Citrus canker, caused by Xanthomonas citri subsp. citri (Xcc), is one of the mayor diseases producing great economic losses worldwide. Xcc invades the host leaf mesophyll tissue through natural openings and can also survive as an epiphyte. We have focused on the identification of Xcc genes involved in virulence factor production and its regulation. Biofilm formation, xanthan and cyclic β-(1,2)-glucan play a key role in epiphytic fitness and canker development. The Rpf/DSF cell-cell signaling system and the second messenger c-di-GMP were shown to be associated with regulation of xanthan and cyclic β-(1,2)-glucan synthesis and in processes such as motility and chemotaxis. Through a collection of Xcc mutants, we have underscored, at least in part, the multifactorial genetic program underlying the establishment of biofilm and pathogenicity of Xcc in citrus plants.